Best Practices for Sterile and Hazardous Drugs Compounding

History of Sterile Compounding (1 hr ACPE credit) 

Learn about the evolution of pharmacy compounding and the development of national standards of practice. 

Determining USP 797 Beyond-Use Dating (1 hr ACPE credit) 

Review USP requirements around beyond-use dating (BUD) and recognize the risk of microbiological contamination in compounded sterile products. 

Quality Releases and Final Checks for Sterile Compounding (1 hr ACPE credit) 

Learn about the requirements set out by USP 797 for release inspections and testing, including visual inspection, sterility testing, and bacterial endotoxins testing. 

USP 797 CSP Handling: Staging through Transport (1 hr ACPE credit) 

Consider unique factors when advancing a CSP from staging to transport, including numerous opportunities where mistakes can be made, and how robust procedures can help prevent errors. 

Master Formulation and Compounding Records for Sterile Compounding (1 hr ACPE credit) 

Use compounding documentation to provide evidence of procedures or activities performed during compounding, such as compounding instructions, equipment required, and calculations. 

Standard Operating Procedures for Sterile Compounding (1 hr ACPE credit) 

Recognize the importance of standard operating procedures (SOPs) to ensure the preparation of medication is reproducible and reduce preventable errors and patient injuries. 

General Elements of Documentation for Sterile Compounding (1 hr ACPE credit) 

Review key elements of good documentation, including USP 797 requirements, and why it’s important to maintain good documentation at your compounding facility. 

Use of Equipment and Integrating Technology for Sterile Compounding (1 hr ACPE credit) 

Recognize how to utilize automated compounding devices (ACDs) for sterile compounding and the techniques and work practices that must be implemented to minimize microbiological contamination of compounded sterile preparations. 

Hazardous Drug Overview (1 hr ACPE credit) 

Learn about health and occupational risks of exposure to hazardous drugs and strategies to implement for safe handling of hazardous drugs. 

Containment Primary and Secondary Engineering Controls (USP 795 and 797) (1 hr ACPE credit) 

Learn how containment engineering controls operate and function to protect you from hazardous drugs and their potentially damaging effects. 

Personal Protective Equipment for HD Handling for USP 795 and 797 Compounding (1 hr ACPE credit) 

Review the more complex garbing required for handling and compounding hazardous drugs. 

HD Work Practice: Receiving through Transport to Patients (1 hr ACPE credit) 

Review required and best practices for handling hazardous drugs, including containment of residue, packaging, and transporting compounded preparations. 

HD Work Practice: Decontamination and Spill Management (USP 795 and 797) (1 hr ACPE credit) 

Learn about decontamination in hazardous drug handling environments, managing spills and disposing of hazardous drugs, and documentation requirements. 

Sterile Compounding Contamination Control Principles (0.75 hr ACPE credit) 

Achieve a practical understanding of the importance of contamination control principles and how workflow activity challenges the microbial state of control in sterile compounding environments. 

Sterile-to-Sterile Compounding (1.25 hr ACPE credit) 

Gain knowledge about newly required components of sterile compounding practices, including beyond-use dating, drug testing, and stability and quality release testing. 

Sterile Compounding Documentation (0.5 hr ACPE credit) 

Learn about the importance of documentation and the required components of successfully documenting compounding processes. 

Secondary Engineering Controls for Nonhazardous Sterile Compounding (1.5 hr ACPE credit) 

Learn the minimum USP chapter requirements for engineering controls and distinguish best practices for facility-specific designs that achieve operational compliance rather than just meeting regulatory compliance. 

Hand Hygiene and Garbing for Sterile Compounding (1 hr ACPE credit) 

Review key elements of effective hand hygiene and garbing as required by USP 797. 

USP 797 Material Handling (0.5 hr ACPE credit) 

Explore elements of contamination control that emphasize the movement of supplies and materials into controlled areas. 

USP 797 Personnel Sampling (1.25 hr ACPE credit) 

Examine the expanded compliance requirements now outlined in USP 797, including documentation, competency evaluation, and the development of a personnel sampling program as determined by the designated person. 

Primary Engineering Controls for Nonhazardous Sterile Compounding (1 hr ACPE credit) 

Receive a practical understanding of primary engineering controls (PECs), how they function by design, and how we must operate within the inherent limitations all PECs have in sterile compounding facilities. 

Aseptic Work Practices Overview for Sterile Compounding (0.75 hr ACPE credit) 

Learn about critical elements of aseptic work practices to use in sterile compounding. 

Testing and Certification of PECs and SECs (USP 797) (1.25 hr ACPE credit) 

Increase your confidence when engaging in conversations with certifiers regarding certification testing and documentation. Learn required and best practice elements of reporting to ensure quality and USP chapter compliance. 

Sterility and Bacterial Endotoxin Testing Specific to USP 797 (0.75 hr ACPE credit) 

Acquire a deeper understanding of USP 71 and elements of sterility testing, rapid microbial testing (RMT), and bacterial endotoxin testing (BET). 

Sanitization of Sterile Compounding PECs and SECs (1.25 hr ACPE credit) 

Learn more about how daily and monthly cleaning along with ongoing sanitization processes works to ensure the safety of the compounding environment. 

Environmental Monitoring (1 hr ACPE credit) 

Review key requirements of an environmental monitoring program and how to perform a proper investigation and remediation process in the event of an exceeded action level. 

Quality Systems for Sterile Compounding (1 hr ACPE credit) 

Learn more about the development and implementation of a sterile compounding quality assurance (QA) and quality control (QC) program. 

Overview of USP 800 and HD Handling for Sterile and Nonsterile Compounding (0.75 hr ACPE credit) 

Draw a conclusion to the relationship between recommended practice and guidelines and how they all had an influence in the development of USP 800 and how they all apply to worker and patient safety as well as practical awareness to the potential exposure of hazardous drugs. 

Assessment of Risk for Sterile and Nonsterile HD Compounding (0.75 hr ACPE credit) 

Learn about hazardous medications that may be exempted from USP 800 full containment practices and explore strategies to perform assessments of risk. 

C-SECs for Sterile and Nonsterile Hazardous Drug Compounding (0.75 hr ACPE credit) 

Learn the minimum USP chapter requirements for containment engineering controls in hazardous drug environments and determine what best practices for facility-specific designs are most appropriate for your pharmacy practice. 

C-PECs for Sterile and Nonsterile Hazardous Drug Compounding (0.75 hr ACPE credit) 

Distinguish the different types of C-PECs used in HD compounding settings and understand how they operate based on their individual design. 

Response to HD Exposure and Spills (USP 795 and 797) (0.5 hr ACPE credit) 

Learn about the critical elements of an exposure control and response plan, including elements of proper handling of hazardous medication spills. 

Donning, Doffing, and PPE for Sterile and Nonsterile HD Compounding (0.75 hr ACPE credit) 

Review the steps for properly donning and doffing hazardous medication PPE. 

USP 800 Sterile Compounding Work Practice Strategies (0.75 hr ACPE credit) 

Learn work practice strategies for handling hazardous medication to minimize the spread of HD contamination. 

Wipe Sampling and CSTDs for Sterile and Nonsterile Hazardous Drug Compounding (0.25 hr ACPE credit) 

Explore wipe sampling and the use of closed system transfer devices in reducing the migration of hazardous medication residue out of controlled areas. 

Decontamination and Cleaning in HD Environments (USP 795 and 797) (0.75 hr ACPE credit) 

Examine the framework of decontamination, cleaning, and disinfection according to USP 800 and compare these steps to USP 797 requirements. Apply recommended best practices for developing effective steps to manage HD contamination at a safe level

Best Work Practices & Identifying Insanitary Conditions (3 hr live, ACPE credit) 

Learn about elements that make up best work practices and how to identify insanitary conditions within a sterile compounding area. 

Focus on Hazardous Drugs (2 hr live, ACPE credit) 

Review key areas of consideration regarding hazardous drugs, including additional items that must be accounted for.