prescription bottles with pills

RxAdvanced: Opioid Stewardship

Reduce risk of opioid addiction and overdose.

$199 / year

Course Overview:


CE Hours: 12 hours

Expiration: September 30, 2025

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Program Overview

Pharmacists are influential links for safe, appropriate use of opioid prescriptions.

RxAdvanced: Opioid Stewardship prepares pharmacists in healthcare institutions of all sizes to make confident, standards-based decisions about managing pain in an acute care setting while reducing the risk of opioid addiction and overdose. We created RxAdvanced: Opioid Stewardship training to help pharmacists advance their knowledge of best practices in opioid stewardship with the latest clinical research in opioid management and techniques and guidelines that can reduce opioid risks and improve follow-up care. 

Course Curriculum

Discuss the assessment of pain, pharmacological agents used as components of multimodal analgesic (MMA) regimens, and the rationale for and application of opioid-sparing pain management approaches. 

  • ACPE Course #: JA0006454-0000-22-3071-H08-P
  • CE Credit: 1.5 hours

Reviews the opioid crisis and the role of prescription opioids. Receive an introduction to opioid stewardship. 

  • ACPE Course #: JA0006454-0000-22-3072-H08-P
  • CE Credit: 0.5 hour


Address the evidence behind stewardship programs, how to build a team, and tangible first steps a program should take.

  • ACPE Course #: JA0006454-0000-22-3073-H08-P
  • CE Credit: 1 hour


Learn how data can support opioid stewardship. Gather tips for tracking and sharing data, identify appropriate quality measures, and review the current evidence for using clinical decision support to improve these measures.

  • ACPE Course #: JA0006454-0000-22-3074-H08-P
  • CE Credit: 1 hour

Perform opioid conversion calculations and review proper application of each calculation including conversions on and off of patient-controlled analgesia (PCA) pumps.

  • ACPE Course #: JA0006454-0000-22-3075-H08-P
  • CE Credit: 1 hour


Focus on treating pain in pancreatitis and sickle cell disease. Review pain treatment in palliative care and the emergency department.

  • ACPE Course #: JA0006454-0000-22-3076-H08-P
  • CE Credit: 1 hour


Discusses the clinical complexity of managing acute pain for patients admitted to the hospital presenting with chronic opioid use, either as medication for opioid use disorder or for chronic pain management.

  • ACPE Course #: JA0006454-0000-22-3077-H08-P
  • CE Credit: 1 hour

Discusses several mitigation strategies that exist for managing opioid-related adverse events, which are common and often preventable.

  • ACPE Course #: JA0006454-0000-22-3078-H08-P
  • CE Credit: 1.5 hours


Discusses pain management approaches unique to patients undergoing surgical procedures and their implications for pharmacist practice. Review medication-related components of clinical practice guidelines and primary literature that guide postoperative pain management and opioid stewardship, including enhanced recovery protocols, regional anesthesia, and postoperative discharge analgesic prescribing.

  • ACPE Course #: JA0006454-0000-22-3079-H08-P
  • CE Credit: 1.5 hours


Review opioid use disorder (OUD) pathophysiology, treatment, withdrawal, and psychosocial interventions in a variety of patients, including those who are pregnant or have concomitant psychiatric disorders.

  • ACPE Course #: JA0006454-0000-22-3080-H08-P
  • CE Credit: 1 hour


Addresses issues pertinent to analgesic medication reconciliation for chronic pain patients and post-operative patients in a hospital setting when transitioning to discharge. Discuss risk mitigation strategies for hospitalized patients including opioid taper strategies, naloxone use, and post-discharge follow-up and monitoring for patients on opioids when pain becomes chronic.

  • ACPE Course #: JA0006454-0000-22-3081-H08-P
  • CE Credit: 1 hour

What To Expect

RxAdvanced: Opioid Stewardship is a 12-hour ACPE-accredited CE program created by leading experts based on the latest research and guidelines to help pharmacists become leaders in opioid stewardship while reducing the risk of opioid addiction and overdose. Printable clinical resources help pharmacists apply knowledge to practice. Pharmacists can complete each course within the program online at their convenience 24/7.

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Key Benefits

  • Cost-effective training that delivers CE credits
  • Interactive, multimedia courses created by leading experts based on the latest research and guidelines, available online 24/7
  • Meets national standards with the latest clinical research in opioid management, as well as new and revised CDC guidelines for prescribing opioids for pain
  • Enhanced clinical expertise as pharmacists are trained to recognize risks for adverse effects from opioid prescriptions and better equipped to plan and influence safe, effective pain management for a wide range of patients

RxAdvanced FAQ

RxAdvanced gives pharmacists an edge with efficient, relevant, affordable training to help deepen knowledge and practical skills in critical subjects. RxAdvanced also helps pharmacy leaders and administrators ensure and document staff competency with assignments, completion reports, benchmark reports, and more.
Most programs are $199; Hazardous Drugs is $99. Bulk pricing with discounts is available for enterprise clients, including an “All Access” option.
Yes, pharmacists earn ACPE CE credit for each course they complete in each program. Programs range from 5-16 hours. See program details for more information.
You have access for 12 months from the date of purchase. Courses must be completed before access expires.
Once an RxAdvanced program is completed, you will receive a printable Statement of Completion for the program. You can list your completed training on LinkedIn, Doximity, or other professional networking profile.
Each program is reviewed annually for critical guideline updates, and we release new program versions every 2-3 years. Pharmacists who purchase directly through our website will get the latest version at the time of purchase. Pharmacy leaders who purchase an enterprise subscription will be notified before we move any staff to the latest version.
At this time, RxAdvanced is designed specifically for pharmacists, with recommendations for medication management, patient counseling, and more. Pharmacy leaders who purchase an enterprise subscription may elect to assign only the Sterile Compounding and Hazardous Drugs programs to pharmacy technicians.